DNA double helix
Physics
Mean stretch0.0%
Replication forkOpening
Helicase opens. Polymerase copies.
0 / 12 opened0 / 24 copied
HelicasePolymeraseNew DNA
Template read 3′ → 5′New DNA grows 5′ → 3′
Leading: continuous · Lagging: fragmentsPrimers assumed; fragment joining simplified.
Helicase unzips
Leading polymerase ↑ synthesis 5′ → 3′
Lagging polymerase ↓ synthesis 5′ → 3′
New leading strand 5′ bottom · 3′ growing end ↑
New lagging fragments 5′ top · 3′ growing end ↓
↑ Template read 3′ → 5′
↓ Template read 3′ → 5′
Daughter DNA 1 One original + one new strand
Daughter DNA 2 One original + one new strand
SequencePair 06 · T–A
5′
3′3′
5′
3′3′
5′
Select a pair to inspect2 / 2 bonds
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CNOH
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